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Hello, everyone. Damian here with the latest biotech startup to downsize, a novel idea in cancer treatment, and a few major catalysts on the calendar.

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The need-to-know this morning

  • Kyverna Therapeutics, a biotech developing CAR-T treatments for autoimmune diseases, filed for an initial public offering. Its lead product, called KYV-101, is a patient-specific, CD19-targeted cell therapy for lupus nephritis, currently in a mid-stage clinical trial.

A buzzy biotech cuts staff, acknowledges setbacks

Dewpoint Therapeutics, a biotech startup that has raised nearly $300 million, has laid off 15% of its staff and acknowledged a pair of high-profile partnerships fell apart.

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